| Actor | Dennis Hopper (as Dr. Luther Waxling), Griffin Dunne (as Martin Mirkheim), Christopher Walken (as Kim Ulander), John Turturro (as Ron), Ethan Hawke (as Roger), David Thornton (as Rob), Martin Scorsese (as The Accountant), Vincent Angell (as Security Guard), Dan Hedaya (as Tailor), Robert Knepper (as Daniel Strong), Jason Ferraro (as Young Daniel Strong), Angel David (as Panfilo ), Randy Pearlstein (as Desk Clerk), Kenneth Simmons (as Nunez), Frank Girardeau (as State Trooper), Sergio Kato (as Security Guard) |
| Actress | Rosanna Arquette (as Lauren Mirkheim), Illeana Douglas (as Marie Davenport), Tahnee Welch (as Dead World Girl), Linda Wahl (as Party Guest), Laurie Godet (as Model), Nicole Burdette (as Dorothy), Tanya Pohlkotte (as Kim's Secretary), Karole Armitage (as Red River Valley Dancer), Joli Julianna (as Esema Strong) |
| Associate Producer | Mark Blum, Boaz Davidson, Trevor Short |
| Cinematography By | Bobby Bukowski, Michael Spiller |
| Director | David Salle |
| Executive Producer | Danny Dimbort, Avi Lerner, Martin Scorsese |
| Film Editing By | Lawrence Blume, Michelle Gorchow |
| Music By | Elmer Bernstein |
| Producer | Ruth Charny, Elie Cohn, Dan Lupovitz |
| Writer | Howard Korder |
| Writer (Screenplay) | Michael Almereyda |
