| Actor | David Dukes (as Wade Halsey), Robert Klein (as Big Al Barker), Ed Marinaro (as Mitch Margolis), Mark Frankel (as Simon Bolt), George Clooney (as James Falconer), Stephen Collins (as Dr. Gabriel Sorenson), Garrett M. Brown (as John Whitsig), Ryan Francis (as Trevor Whitsig), Dustin Berkowitz (as Evan Whitsig), Sean Nelson (as Jesse Bayliss) |
| Actress | Swoosie Kurtz (as Alexandra "Alex" Reed Halsey Barker), Sela Ward (as Theodora "Teddy" Reed Margolis Falconer Sorenson), Patricia Kalember (as Georgiana "Georgie" Reed Whitsig), Jo Anderson (as Dr. Charlotte "Charley" Bennett Hayes (recurring; seasons 4-5)), Sheila Kelley (as Dr. Charlotte "Charley" Bennett Hayes (season 6)), Elizabeth Hoffman (as Beatrice Reed Ventner), Heather McAdam (as Cat Margolis), Kathy Wagner (as Reed Halsey Philby #1 (Season 1)), Ashley Judd (as Reed Halsey Philby #2 (Seasons 2-4)), Noelle Parker (as Reed Halsey Philby #3 (Season 6)), Kathryn Zaremba (as Roxie Whatley), Caroline McWilliams (as Grace Whatley) |
| Broadcaster | National Broadcasting Corporation (NBC)* |
| Creator | Ron Cowen, Daniel Lipman |
| Distributor | Warner Bros. Television Distribution |
| Production Company | Cowlip Productions |
| Production Company (1991–1993) | Lorimar Television |
| Production Company (1993–1996) | Warner Bros. Television |
| Links | https://en.wikipedia.org/wiki/Sisters_(American_TV_series) · https://www.imdb.com/title/tt0101199/?ref_=nm_flmg_act_2 |
Added by MissBabyGirl