| Audio | Mono |
| Subtitles | English SDH, Français & Español |
| Languages | English |
| Aspect Ratio | 16:9, 1.85:1 |
| Color | Color |
| Video Standard | NTSC |
| Packaging | Keep case (Standard Clear Blue Blu-Ray Case) |
| Classification | MPAA G |
| Barcode | 8 83929 11587 7 |
| Catalog Number | 2000037631 |
| ISBN | 1-4198-9582-6 |
| Brand | Warner Home Video |
| Company | DTS, Inc., Dolby Laboratories Licensing Corporation, Blu-ray Disc Association |
| Copyright | Warner Bros. Entertainment Inc. |
| Distribution | Warner Home Video |
| Film Company | Warner Bros. Pictures |
| Territory | United States |
| Notes | What's Up Doc? released on the Blu-ray format in the US.
Special Features:
-Scene-Specific Commentary by Barbara Streisand
-Full-Movie Commentary by Director Peter Bogdanovich
-Vintage Featurette "Screwball Comedies...Remember Them?"
-Theatrical Trailer |
